Information

Areas of Research Interest

I am a mammalian reproductive biologist with a fundamental interest in ovarian function. This includes: the mechanisms underlying folliculogenesis focusing on the role of somatic cells in regulating this process; factors governing early embryo development; clinical infertility; and ovarian cancer. I am part of a NIH-funded Program Project investigating the differential activity and function of human FSH glycoforms upon reproductive function and how these glycoforms change as a function of age. Numerous techniques are utilized to address the above research areas including primary cell culture, molecular biology, biochemistry, and morphological analysis.

Areas of Teaching Interest

Courses Taught Previously

   
BIOL 210 General Biology I
BIOL 420 Molecular Cell Biology
BIOL 526 Endocrinology
BIOL 540 Developmental Biology
BIOL 590 Immunobiology
BIOL 626/640 Reproductive Biology

 

Publications
  1. Bousfield, G. R., May, J. V., Davis, J. S., Dias, J. A., & Kumar, T. R. 2018. In vivo and in vitro impact of carbohydrate variation on follicle-stimulating hormone function. Front. Endocrinol., 9, 216.
  2. Wang, H., May, J., Shuai, B., May, J. V., Bousfield, G. R., & Kumar, T. R. 2016. Evaluation of in vivo bioactivities of recombiant hypo-(FSH21/18) and fully- (FSH24) glycosylated human FSH glycoforms in Fshb null mice. Mol. Cell. Endocrinol., 437, 224-236.
  3. Jiang, C., Hou, X., Wang, C., May, J. V., Butnev, V. Y., Bousfield, G. R., & Davis, J. S. 2015. Hypo-glycosylated hFSH has greater bioactivity than fully-glycosylated recombinant hFSH in human granulosa cells. J. Clin. Endocrinol. Metab., 100(6), e852-E860.
  4. Butnev, V. Y., Butnev, V. Y., May, J. V., Shuai, B., Tran, P., White, W. K., & Bousfield, G. R. Production, purification, and characterization of recombinant hFSH glycoforms for functional studies. Mol. Cell. Endocrinol., 405, 41-52.
  5. Davis, J. S., Kumar, T. R., May, J. V., & Bousfield, G. R. 2014. Naturally occurring follicle-stimulating hormone glycosylation variants. J. Glycomics Lipidomics, 4, e117.
  6. Bousfield, G.R., Butnev, V.Y., Butnev, V.Y., Hiromasa, Y., Harvey, D.J., & May, J.V. 2014. Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24). Mol. Cell. Endocrinol., 382, 989-997.
  7. Alwis, I.D., Maroni, D.M., Hendry, I.R., Roy, S.K., May, J.V., Leavitt, W.W., & Hendry, W.J., 2011. Neonatal Diethylstilbestrol Exposure Disrupts Female Reproductive Tract Structure/Function Via Both Direct And Indirect Mechanisms In The Hamster.  Reprod. Toxicol., 32(4), 472-483.
Professional Experience

 

Year(s) Position Held
2002 - 2009 Associate Professor, Dept. of Biological Sciences, 成人头条, 成人头条, KS
2002 - 2004 Executive Director, H.L. Snyder Medical Research Institute, Winfield, KS
1993 - 2002 Scientific Director, The Women's Research Institute, 成人头条, KS
1987 - 2002 Senior Scientist, The Women's Research Institute, 成人头条, KS
1991 - 2002 Associate Professor, Dept. of Ob/Gyn, Un. of KS School of Medicine-成人头条, 成人头条, KS
1995 - 2002 Adjunct Professor, Dept. of Biological Sciences, 成人头条, 成人头条, KS
1988 - 1997 Director, Assisted Reproductive Technology Lab, The Center for Reproductive Medicine, Univ. of KS School of Medicine-成人头条, 成人头条, KS
1987 - 1991 Assistant Professor, Dept. of Ob/Gyn, Univ. of KS School of Medicine-成人头条, 成人头条, KS
1982 - 1987 Assistant Professor of Ob/Gyn (non-tenure track) and Assistant Professor of Physiology, Duke University Medical Center, Durham, NC

 

Awards and Honors

Honors and Other Activities

Kansas-IDEA Network of Biomedical Research Excellence (K-INBRE): Faculty Scholar Award, 3/1/2007
NIH Study Section- Regular, 4-year Membership:
Previous - RAG, 10/15/2008 鈥 6/30/2012, extended through 2013
Previous - REB , 09/12/1994-06/30/1998

NIH Ad Hoc Member: RAG, 6/25-26/2007; ICER, 10/5-6/2006; CMIR, 6/21-22/2004; REB, 06/02-04/2003, 10/04-06/1993; 6/23-23/1993; BCE, 05/10-12/1992

NIH Special Study Sections: Cooperative Specialized Infertility Research Center Program (U-54), NICHD, 4/8-11/1996; P-50 Site Visit Team DRG, NIH 9/28-30/1995; Special Emphasis Panel, NICHD, NIH, 4/24/1998; Special Emphasis Panel, CSR, NIH, SBIR/STTR Grant Review, 3/29-30/1999 and 11/15-16/1999, Special Emphasis Review Panel, K08 grant review, 7/31/2002.

NIH Ad Hoc Grant Reviewer: MABS, 3/2005, 10/2005, 10/2006; EMNR-A02M, 10/2005; BCE, 12/1989, 5/1991.

Grant Reviewer: USDA 04/1990, 05/1991; and NSF 09/19/90.

Editorial Board: Endocrinology 1993-1996; American Journal of Physiology (Endocrinology/Metabolism) 1995-1997, 1998-2002

Consultant: Food and Drug Administration, DHHS, Ob/Gyn Devices Panel, 1996-2004

High Complexity Clinical Lab Director (HCLD) The American Board of Bioanalysis, 1994-2000

Laboratory Inspector, Reproductive Accreditation Program, College of American Pathologists, 1993-1996

Grants

 

         
Grant #: 5P01-AG029531-07
[NIH, NIA] (Bousfield, PI)
09/01/17 - 05/31/22 Title: The Aging Pituitary/Gonadal Axis $1,709,158
/5 yr
Roles: Co-Leader, Core A-Administrative Core
Leader, Core B - FSH Preparation, Purification and Analysis Laboratory
K-INBRE Core Facility Award 05/10/19 - 04/30/20 Title: WSU P01 Core Lab Cell Counter $8,018 Role: Principal Investigator
K-INBRE Core Facility Award 05/01/17 - 04/30/18 Title: WSU P01 Core Lab Ultralow -80C Freezer $10,081 Role: Principal Investigator
Grant #: 5P01-AG029531-02
[NIH, NIA] (Bousfield, PI)
03/01/09 - 02/28/14 Title: The Aging Pituitary/Gonadal Axis $6,622,855
/5 yr
Roles: Co-Leader, Core A-Administrative Core
Leader, Core B - FSH Preparation, Purification and Analysis Laboratory

K-INBRE  Translational Parnershp Pair Grant

04/01/12 - 03/31/13

Diagnostic Relevance of Human Urinary FSH Glycoform Assessment to Ovarian Aging

$37,500 Role: Principal Investigator
K-INBRE Core Facility Grant 05/01/11 - 04/30/12 Title: WSU P01 Core Lab Roller Bottle Incubator $18,557 Role: Principal Investigator
Grant #:
1G20RR031092-01
[NCRR] (Hendry, PI)
07/01/10 - 06/30/11 Title: 成人头条 Combined Core Facility Renovation Project $2,109,094
/2 yr.
Role: Grant Proposal Author & Project Manager. The application was organizae and written entirely by Dr. May who is responsible for progress and completion of the project.

 

Additional Information
  • Adjunct Associate Professor, Dept. of Medical Sciences, School of Medicine-成人头条, University of Kansas Medical Center, 成人头条, Kansas

Education
Institute Degree Year Field of Study
University of Maine BS 1970 Biochemistry
University of Rhode Island PhD 1979 Biochemistry
Duke University Medical Center Postdoctoral Fellowship 1979-1982 Reproductive Biology